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Scientist of the Invisible

Too much ammunition lately, not enough self-control.

Regulation of pokemon 1 activity by sumoylation

Natuurkundigen zijn er om berucht, maar ook moleculair biologen hebben last van nerderige humor als het om naamgeving gaat. Hier wordt bijvoorbeeld onderzocht of het eiwit Pokemon 1 het eiwit SUMO kan binden:
Pokemon 1 is a proto-oncogenic transcriptional regulator that contains a POZ domain at the N-terminus and four Kruppel-like zinc fingers at the C-terminus. Pokemon 1 plays an important role in adipogenesis, osteogenesis, oncogenesis, and transcription of NF-kB responsive genes. Recent reports have shown that biological activities of transcription factors are regulated by sumoylation. We investigated whether Pokemon 1 is post-translationally modified by sumoylation and whether the modification affects Pokemon 1's transcriptional properties. We found that Pokemon 1 is sumoylated in vitro and in vivo.


Ben je meer van de Sega dan van de Nintendo, wees gerust: er is ook een Sonic Hedgehog.
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9:51 a.m.

Beide links zijn, abusievelijk naar ik aanneem, eender.

posted by Blogger martijn on 9:51 a.m.
 



4:07 p.m.

Beetje laat, maar je kan nu alsnog lezen over Sonic Hedgehog en Snail.

posted by Blogger Martijn on 4:07 p.m.
 



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